Hydroxypropyl Methyl Cellulose (HPMC)
Chemical Description
-- Hydroxypropylmethyl Cellulose (abbr. HPMC)
■ CAS No. 9004-65-3
■ Molecular and Structural Formula C12H20O10
■ Characteristics
-- A white to yellow powder or granular product;
-- Nearly insoluble in anhydrous ethanol, ethyl ether and acetone;
■ Specification
NO |
Item |
60MT(2910) |
65MT(29.6) |
75MT(2208) |
1 |
Methoxy % |
28.0-30.0 |
27.0-30.0 |
19.0-24.0 |
2 |
Hydroxypropyoxyl % |
7.0-12.0 |
4.0-7.5 |
4.0-12.0 |
3 |
Gelation temperature oC |
58.0-64.0 |
62.0-68.0 |
70.0-90.0 |
4 |
Loss on drying % |
≤5.0 |
||
5 |
Residue on ignition % |
≤1.5 |
||
6 |
pH |
4.0-8.0 |
||
7 |
Heavy metals ppm |
≤20 |
||
8 |
Arsenic ppm |
≤2.0 |
■ Application
--Used in tablets for dressing and binding to improve solubility of the drugs and reinforce tablets’ water prevention function
--Mixed suspending agent, additive for eye drops, sustained-release agent and so on;
■ Packaging and Storage
--Packed in 25, 50 kg fiber or plastic drum;
--Stored in dry place at room temperature;
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