Hyaluronic Acid

■ Chemical Description

-- Hyaluronic Acid 

■ CAS No. 9004-61-9

■ Molecular and Structural Formula C₂₈H₄₄N₂O₂₃

■ Characteristics

-- White or almost white, very hygroscopic grain or powder, without odor;

-- Clear solution when dissolved in water; insoluble in ethanol, acetone and aether;

■ Specification

No	Tests	Specification
		Food grade	Cosmetics grade	Pharmaceutical grade
1	pH(0.1% water solution)	6.0-7.5	6.0-7.5	6.0-7.5
2	Transparency %	--	≥99.0
3	Molecular weight	Practical value	≥1.00×106	0.8-2.0×106
4	Loss on drying %	≤10.0	≤10.0	≤8.0
5	Kinematic viscosity	--	Practical value
6	Pesidue on ignition %	≤13.0	--	＜15.0
7	Protein %	--	≤0.1	≤0.05
8	Heavy metals(as Pb) ug/g	≤20	≤20	＜10
9	Arsenicum ug/g	≤2	--	＜2
10	Glucuronic acid %	≥42.0	≥44.0	≥45.0
11	Sodium Hyaluronate	--	≥91.0
12	Bacteria counts cfu/g	≤100	＜10
13	Mold&Yeast cfu/g	≤100	＜10
14	Escherichia coli	negative	--
15	Staphylococcus aureus	negative	Negative

■ Application

--Water retention and lubrication in other tissues and organs, such as joint cavity, blood vessel, heart and brain. Decrease of HA level of these tissues can result in arthritis, arteriosclerosis, pulse disorder and brain atrophy;

■ Packaging and Storage

--Packed in 25, 50 kg fiber or plastic drum, inner lined with PE bags;

--Stored in dry place at room temperature;

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