PVP-K HOMOPOLYMER SERIES

Chemical Description

--Polyvinylpyrrolidone (abbr. PVP)

■ CAS No. 9003-39-8

■ INCI Name  PVP

■ Molecular and Structural Formula (C₆H₉NO)n

 

■ Characteristics

--A white to yellowish white , hygroscopic powder;

--Freely soluble in water and a variety of organic solvents;

■ Specification Ph Eur ,USP/NF,BP,JP

No	Tests	K15	K17	K25	K30	K90
1	Identification, A B C D E	Complies
2	Appearance of solution	Clear, ≤B6,BY6 or R6
3	PH(in 5% solution)	3-5	3-5	3-5	3-5	4-7
4	Viscosity, as K-value	13-17	14.5-19.5	22.5-27	27-32.4	81-97
5	Aldehyde, ppm	≤500	≤500	≤500	≤500	≤500
6	Peroxides (as H2O2), ppm	≤400	≤400	≤400	≤400	≤400
7	Formic acid,%	≤0.5	≤0.5	≤0.5	≤0.5	≤0.5
8	Hydrazine, ppm	≤1	≤1	≤1	≤1	≤1
9	Impurity A (VP),ppm	≤10	≤10	≤10	≤10	≤10
10	Impurity B (2-pyrrolidone ),%	≤3.0	≤3.0	≤3.0	≤3.0	≤3.0
11	Heavy metals, ppm	≤10	≤10	≤10	≤10	≤10
12	Water, %	≤5.0	≤5.0	≤5.0	≤5.0	≤5.0
13	Sulphated ash,%	≤0.1	≤0.1	≤0.1	≤0.1	≤0.1
14	Assay, as Nitrogen content,%	11.5-12.8	11.5-12.8	11.5-12.8	11.5-12.8	11.5-12.8

■ Application

--Binder for tablets, granules and hard gelatin capsules;

--Bioavailability enhencement, Film formation, Solubilization;

--Injection preparations, Stabilization of suspensions, Drug stabilization;

--Dietetic tablets in neutritional products;

■ Packaging and Storage

--Packed in 25, 50 kg fiber or plastic drum, inner lined with PE bags;

--Stored in dry place at room temperature;

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