Hydroxypropyl Methyl Cellulose (HPMC)

Chemical Description

-- Hydroxypropylmethyl Cellulose (abbr. HPMC)

■ CAS No. 9004-65-3

■ Molecular and Structural Formula C12H20O₁₀

■ Characteristics

-- A white to yellow powder or granular product;

-- Nearly insoluble in anhydrous ethanol, ethyl ether and acetone;

■ Specification

NO	Item	60MT(2910)	65MT(29.6)	75MT(2208)
1	Methoxy %	28.0-30.0	27.0-30.0	19.0-24.0
2	Hydroxypropyoxyl %	7.0-12.0	4.0-7.5	4.0-12.0
3	Gelation temperature oC	58.0-64.0	62.0-68.0	70.0-90.0
4	Loss on drying %	≤5.0
5	Residue on ignition %	≤1.5
6	pH	4.0-8.0
7	Heavy metals ppm	≤20
8	Arsenic ppm	≤2.0

■ Application

--Used in tablets for dressing and binding to improve solubility of the drugs and reinforce tablets’ water prevention function

--Mixed suspending agent, additive for eye drops, sustained-release agent and so on;

■ Packaging and Storage

--Packed in 25, 50 kg fiber or plastic drum;

--Stored in dry place at room temperature;

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